SOFA Score Calculator — Sequential Organ Failure Assessment
The Sequential Organ Failure Assessment (SOFA) score quantifies the degree of organ dysfunction in critically ill patients across six systems — respiratory, coagulation, liver, cardiovascular, CNS, and renal — each rated 0–4. Select the worst observed value in each system over the past 24 hours.
Respiratory (PaO₂/FiO₂)
Coagulation (Platelets)
Liver (Bilirubin)
Cardiovascular (MAP / Vasopressors)
CNS (Glasgow Coma Score)
Renal (Creatinine / Urine Output)
Total score: 0 (no dysfunction) to 24 (maximal failure in all systems)
- 1
Resp + Coag + Liver subscores
0 + 0 + 0 = 0 - 2
SOFA score (+ Cardio + CNS + Renal)
0 + 0 + 0 + 0 = 0
How does this calculator work?
SOFA sums subscores for respiratory, coagulation, liver, cardiovascular, CNS, and renal function (each 0–4), giving 0–24. Higher scores predict higher ICU mortality: ≤6 is low risk (<10% mortality), 7–12 moderate (~15–40%), and >12 high (>50%). An acute SOFA rise of ≥2 from baseline defines organ dysfunction in sepsis (Sepsis-3 criteria).
Formula
How this is calculated
The SOFA score, published in 1994 and refined for the Sepsis-3 definition in 2016, measures the degree of organ failure in each of six organ systems on a scale of 0 (normal) to 4 (most abnormal). Respiratory dysfunction is gauged by the PaO₂/FiO₂ ratio; coagulation by platelet count; liver function by bilirubin; cardiovascular status by mean arterial pressure and vasopressor requirements; central nervous system function by the Glasgow Coma Score; and renal function by serum creatinine or urine output.
The six subscores are added to give a total from 0 to 24. Higher scores correlate with higher ICU mortality: a score of 0–1 carries less than 10% mortality; scores above 11 are associated with mortality exceeding 50%. The delta-SOFA (change over 48 hours) has additional prognostic value — increasing scores signal deterioration even when the absolute level is not yet alarming.
The simplified SOFA (qSOFA) — used outside the ICU — uses only mental status, respiratory rate, and systolic BP, each scored 0–1. This tool calculates the full SOFA. Always use clinical judgment alongside the score; it is a risk-stratification and communication tool, not a treatment decision by itself.
Frequently asked questions
The SOFA score quantifies the degree of organ failure in ICU patients, helps predict mortality, and forms part of the Sepsis-3 definition (organ dysfunction identified by an acute increase in the SOFA score of ≥2 points due to infection). Serial scores over time are more informative than a single reading.
The Sepsis-3 consensus (2016) defines sepsis as life-threatening organ dysfunction caused by a dysregulated host response to infection, operationalised as an acute SOFA increase of ≥2 in a patient with suspected infection. There is no fixed absolute threshold; the change from baseline matters most.
qSOFA (quick SOFA) is a simplified 3-item bedside screen for sepsis risk outside the ICU: altered mental status (GCS <15), respiratory rate ≥22/min, and systolic BP ≤100 mmHg — each 0 or 1. A score of ≥2 suggests high risk. The full SOFA is used inside the ICU and requires lab values.
Also known as
TG we-Calculate Editorial Team. (2026). SOFA Score Calculator — Sequential Organ Failure Assessment [Online calculator]. TG we-Calculate. https://we-calculate.com/calculator/sofa-score-calculator
TG we-Calculate Editorial Team. "SOFA Score Calculator — Sequential Organ Failure Assessment." TG we-Calculate. 2026. https://we-calculate.com/calculator/sofa-score-calculator.
TG we-Calculate Editorial Team, "SOFA Score Calculator — Sequential Organ Failure Assessment," TG we-Calculate, 2026. [Online]. Available: https://we-calculate.com/calculator/sofa-score-calculator
@misc{wecalculate_sofa_score_calculator, title = {SOFA Score Calculator — Sequential Organ Failure Assessment}, author = {{TG we-Calculate Editorial Team}}, howpublished = {\url{https://we-calculate.com/calculator/sofa-score-calculator}}, year = {2026}, note = {TG we-Calculate} }
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